6C48.2

ICD-11 MMS 2026-01

Caffeine intoxication

Description

Caffeine intoxication is a clinically significant transient condition that develops during or shortly after the consumption of caffeine that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of caffeine and their intensity is closely related to the amount of caffeine consumed. They are time-limited and abate as caffeine is cleared from the body. Presenting features may include restlessness, anxiety, excitement, insomnia, flushed face, tachycardia, diuresis, gastrointestinal disturbances, muscle twitching, psychomotor agitation, perspiration or chills, and nausea or vomiting. Cardiac arrhythmias may occur. Disturbances typical of intoxication tend to occur at relatively higher doses (e.g., > 1 g per day). Very high doses of caffeine (e.g., > 5 g) can result in respiratory distress or seizures and can be fatal.

Index terms

  • Caffeine intoxication

Exclusions from above levels

  • 6C46 – Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinone
  • QE11.5 – Hazardous use of caffeine
  • QE62 – Uncomplicated bereavement
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  • QE84 – Acute stress reaction

Sibling codes

  • 6C48.0 – Episode of harmful use of caffeine
  • 6C48.1 – Harmful pattern of use of caffeine
  • 6C48.3 – Caffeine withdrawal
  • 6C48.4 – Certain specified caffeine-induced mental or behavioural disorders
  • 6C48.Y – Other specified disorders due to use of caffeine
  • 6C48.Z – Disorders due to use of caffeine, unspecified

Foundation entity

Caffeine intoxication – http://id.who.int/icd/entity/1648213213

Allowed postcoordination axes

Part of: 6C48: Disorders due to use of caffeine › 06: Mental, behavioural or neurodevelopmental disorders