6C48.2ICD-11 MMS 2026-01
Caffeine intoxication
Description
Caffeine intoxication is a clinically significant transient condition that develops during or shortly after the consumption of caffeine that is characterised by disturbances in consciousness, cognition, perception, affect, behaviour, or coordination. These disturbances are caused by the known pharmacological effects of caffeine and their intensity is closely related to the amount of caffeine consumed. They are time-limited and abate as caffeine is cleared from the body. Presenting features may include restlessness, anxiety, excitement, insomnia, flushed face, tachycardia, diuresis, gastrointestinal disturbances, muscle twitching, psychomotor agitation, perspiration or chills, and nausea or vomiting. Cardiac arrhythmias may occur. Disturbances typical of intoxication tend to occur at relatively higher doses (e.g., > 1 g per day). Very high doses of caffeine (e.g., > 5 g) can result in respiratory distress or seizures and can be fatal.
Index terms
- Caffeine intoxication
Exclusions from above levels
6C46– Disorders due to use of stimulants including amphetamines, methamphetamine or methcathinoneQE11.5– Hazardous use of caffeineQE62– Uncomplicated bereavement
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QE84– Acute stress reaction
Sibling codes
6C48.0– Episode of harmful use of caffeine6C48.1– Harmful pattern of use of caffeine6C48.3– Caffeine withdrawal6C48.4– Certain specified caffeine-induced mental or behavioural disorders6C48.Y– Other specified disorders due to use of caffeine6C48.Z– Disorders due to use of caffeine, unspecified
Foundation entity
Caffeine intoxication – http://id.who.int/icd/entity/1648213213
Allowed postcoordination axes
Part of: 6C48: Disorders due to use of caffeine › 06: Mental, behavioural or neurodevelopmental disorders