Progressive supranuclear palsy

Description

Progressive supranuclear palsy (PSP) is a late-onset neurodegenerative disease characterised by supranuclear gaze palsy, postural instability, progressive rigidity, and mild dementia. Five clinical variants have been described with clinicopathological correlations: Classical PSP (Richardson's syndrome), and four atypical variants of PSP including PSP-Parkinsonism (PSP-P), PSP-Pure akinesia with gait freezing (PSP-PAGF), PSP-corticobasal syndrome (PSP-CBS), and PSP-progressive non fluent aphasia (PSP-PNFA).

Index terms

Progressive supranuclear palsy
Steele-Richardson-Olszewksi syndrome
Atypical progressive supranuclear palsy

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Progressive supranuclear palsy - corticobasal syndrome
Progressive supranuclear palsy - parkinsonism
Progressive supranuclear palsy - progressive non fluent aphasia
Progressive supranuclear palsy - pure akinesia with gait freezing
Classical progressive supranuclear palsy

Exclusions from above levels

http://id.who.int/icd/entity/1425591047 – Myasthenia gravis or certain specified neuromuscular junction disorders
http://id.who.int/icd/entity/1525792972 – Arthropathies
6A06 – Stereotyped movement disorder

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05 – Endocrine, nutritional or metabolic diseases
18 – Complications of pregnancy, childbirth and the puerperium
19 – Certain conditions originating in the perinatal period
22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

8A00.1Y – Other specified atypical parkinsonism
8A00.1Z – Atypical parkinsonism, unspecified

Foundation entity

Progressive supranuclear palsy – http://id.who.int/icd/entity/1493396558

Allowed postcoordination axes

hasManifestation

Part of: 8A00.1: Atypical parkinsonism › 8A00: Parkinsonism › 08: Diseases of the nervous system