Juvenile myelomonocytic leukaemia

Description

A myelodysplastic/myeloproliferative neoplasm of childhood that is characterised by proliferation principally of the granulocytic and monocytic lineages. Myelomonocytic proliferation is seen in the bone marrow and the blood. The leukemic cells may infiltrate any tissue, however liver, spleen, lymph nodes, skin, and respiratory tract are the most common sites of involvement.

Exclusions from above levels

2E03 – Malignant neoplasm metastasis in bone or bone marrow
http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Child codes

2A42.0 – Juvenile myelomonocytic leukaemia in complete remission
2A42.Y – Other specified juvenile myelomonocytic leukaemia
2A42.Z – Juvenile myelomonocytic leukaemia, unspecified

Sibling codes

2A40 – Chronic myelomonocytic leukaemia
2A41 – Atypical chronic myeloid leukaemia, BCR-ABL1-negative
2A43 – Refractory anaemia with ring sideroblasts associated with marked thrombocytosis
2A44 – Myeloproliferative and myelodysplastic disease, unclassifiable
2A4Y – Other specified myelodysplastic and myeloproliferative neoplasms
2A4Z – Myelodysplastic and myeloproliferative neoplasms, unspecified

Foundation entity

Juvenile myelomonocytic leukaemia – http://id.who.int/icd/entity/1786015803

Allowed postcoordination axes

Part of: 02: Neoplasms