Chronic myelomonocytic leukaemia

Description

A myelodysplastic/myeloproliferative neoplasm which is characterised by persistent monocytosis, absence of a Philadelphia chromosome and BCR/ABL1 fusion gene, fewer than 20 percent blasts in the bone marrow and blood, often myelodysplasia, and absence of PDGFRA or PDGFRB rearrangement.

Index terms

Chronic myelomonocytic leukaemia
CMML - [chronic myelomonocytic leukaemia]
Chronic monocytic leukaemia

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chronic monocytoid leukaemia
chronic myelomonocytic leukaemia without mention of remission
Chronic myelomonocytic leukaemia in complete remission
Chronic myelomonocytic leukaemia with eosinophilia
CMML - [chronic myelomonocytic leukaemia] with eosinophilia
Chronic myelomonocytic leukaemia Type 1
CMML-1 - [chronic myelomonocytic leukaemia Type 1]
Chronic myelomonocytic leukaemia Type 2
CMML-2 - [chronic myelomonocytic leukaemia Type 2]

Inclusions

Chronic monocytic leukaemia

Excludes

2A50 – Myeloid or lymphoid neoplasm associated with PDGFRA rearrangement
2A51 – Myeloid neoplasm associated with PDGFRB rearrangement

Exclusions from above levels

2E03 – Malignant neoplasm metastasis in bone or bone marrow
http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

2A41 – Atypical chronic myeloid leukaemia, BCR-ABL1-negative
2A42 – Juvenile myelomonocytic leukaemia
2A43 – Refractory anaemia with ring sideroblasts associated with marked thrombocytosis
2A44 – Myeloproliferative and myelodysplastic disease, unclassifiable
2A4Y – Other specified myelodysplastic and myeloproliferative neoplasms
2A4Z – Myelodysplastic and myeloproliferative neoplasms, unspecified

Foundation entity

Chronic myelomonocytic leukaemia – http://id.who.int/icd/entity/2073226578

Allowed postcoordination axes

Part of: 02: Neoplasms