8A46

ICD-11 MMS 2026-01

Central demyelination of corpus callosum

Description

This is demyelination, damage to the myelin sheath of neurons, in the corpus callosum.

Index terms

  • Central demyelination of corpus callosum
  • Encephalopathy, callosal demyelinating
  • Marchiafava-Bignami syndrome
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  • Marchiafava disease
  • Marchiafava-Bignami disease

Exclusions from above levels

  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
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  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • 8A40 – Multiple sclerosis
  • 8A41 – Isolated demyelinating syndromes of the central nervous system
  • 8A42 – Acute disseminated encephalomyelitis
  • 8A43 – Neuromyelitis optica
  • 8A44 – Leukodystrophies
  • 8A45 – Secondary white matter disorders
  • 8A4Y – Other specified multiple sclerosis or other white matter disorders
  • 8A4Z – Multiple sclerosis or other white matter disorders, unspecified

Foundation entity

Central demyelination of corpus callosum – http://id.who.int/icd/entity/1441661203

Part of: 08: Diseases of the nervous system