8C74.1

ICD-11 MMS 2026-01

Periodic paralysis

Description

Rare group of neuromuscular disorders that are associated with defects in ion channels. Characterized by intermittent episodes of severe weakness of the limbs usually after heavy exercise, fasting, or high carbohydrate meals. The three major types of inherited periodic paralysis include hypokalemic periodic paralysis, hyperkalemic periodic paralysis, and Andersen–Tawil syndrome.

Exclusions from above levels

  • http://id.who.int/icd/entity/155258022 – Metabolic disorders
  • LD26.41 – Arthrogryposis multiplex congenita
  • 05 – Endocrine, nutritional or metabolic diseases
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  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
  • 22 – Injury, poisoning or certain other consequences of external causes

Child codes

  • 8C74.10 – Hypokalaemic periodic paralysis
  • 8C74.11 – Hyperkalaemic periodic paralysis
  • 8C74.1Y – Other specified periodic paralysis
  • 8C74.1Z – Periodic paralysis, unspecified

Sibling codes

  • 8C74.0 – Paramyotonia congenita
  • 8C74.Y – Other specified periodic paralyses or disorders of muscle membrane excitability
  • 8C74.Z – Periodic paralyses or disorders of muscle membrane excitability, unspecified

Foundation entity

Periodic paralysis – http://id.who.int/icd/entity/577112387

Part of: 8C74: Periodic paralyses or disorders of muscle membrane excitability › 08: Diseases of the nervous system