8C74

ICD-11 MMS 2026-01

Periodic paralyses or disorders of muscle membrane excitability

Description

These are a group of disorders caused by malfunctioning of the ion channels in skeletal muscle membranes causing the cells to depolarize leading to weakness or paralysis. The common triggers include cold, heat, high carbohydrate meals, stress, excitement, physical exertion etc.

Exclusions from above levels

  • http://id.who.int/icd/entity/155258022 – Metabolic disorders
  • LD26.41 – Arthrogryposis multiplex congenita
  • 05 – Endocrine, nutritional or metabolic diseases
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  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
  • 22 – Injury, poisoning or certain other consequences of external causes

Child codes

  • 8C74.0 – Paramyotonia congenita
  • 8C74.1 – Periodic paralysis
  • 8C74.Y – Other specified periodic paralyses or disorders of muscle membrane excitability
  • 8C74.Z – Periodic paralyses or disorders of muscle membrane excitability, unspecified

Sibling codes

  • 8C70 – Muscular dystrophy
  • 8C71 – Myotonic disorders
  • 8C72 – Congenital myopathies
  • 8C73 – Mitochondrial myopathies
  • 8C75 – Distal myopathies
  • 8C76 – Myofibrillar myopathy
  • 8C77 – Ocular myopathy
  • 8C78 – Malignant hyperthermia or hyperpyrexia
  • 8C7Y – Other specified primary disorders of muscles
  • 8C7Z – Primary disorders of muscles, unspecified

Foundation entity

Periodic paralyses or disorders of muscle membrane excitability – http://id.who.int/icd/entity/1222696062

Allowed postcoordination axes

Part of: 08: Diseases of the nervous system