2A81.6

ICD-11 MMS 2026-01

Epstein-Barr Virus-positive diffuse large B-cell lymphoma of the elderly

Description

An aggressive diffuse large B-cell lymphoma affecting patients older than 50 years. Epstein-Barr virus is present in all cases. There is no known history of immunodeficiency or prior lymphoma. The majority of patients present with extranodal disease.

Index terms

  • Epstein-Barr Virus-positive diffuse large B-cell lymphoma of the elderly
  • EBV-positive diffuse large B-cell lymphoma of the elderly

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Sibling codes

  • 2A81.0 – Primary mediastinal large B-cell lymphoma
  • 2A81.1 – Intravascular large B-cell lymphoma
  • 2A81.2 – Plasmablastic lymphoma
  • 2A81.3 – Lymphomatoid granulomatosis
  • 2A81.4 – T-cell/histiocyte rich large B-cell lymphoma
  • 2A81.5 – Primary diffuse large B-cell lymphoma of central nervous system
  • 2A81.7 – Diffuse large B-cell lymphoma associated with chronic inflammation
  • 2A81.8 – ALK-positive large B-cell lymphoma
  • 2A81.9 – Primary effusion lymphoma
  • 2A81.A – Primary cutaneous diffuse large B-cell lymphoma, leg type
  • 2A81.Y – Other specified diffuse large B-cell lymphomas
  • 2A81.Z – Diffuse large B-cell lymphoma, not otherwise specified

Foundation entity

Epstein-Barr Virus-positive diffuse large B-cell lymphoma of the elderly – http://id.who.int/icd/entity/407807101

Allowed postcoordination axes

Part of: 2A81: Diffuse large B-cell lymphomas › 02: Neoplasms