2A81

ICD-11 MMS 2026-01

Diffuse large B-cell lymphomas

Description

Non-Hodgkin lymphomas are characterised by a proliferation of predominantly large neoplastic B lymphocytes.

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Child codes

  • 2A81.0 – Primary mediastinal large B-cell lymphoma
  • 2A81.1 – Intravascular large B-cell lymphoma
  • 2A81.2 – Plasmablastic lymphoma
  • 2A81.3 – Lymphomatoid granulomatosis
  • 2A81.4 – T-cell/histiocyte rich large B-cell lymphoma
  • 2A81.5 – Primary diffuse large B-cell lymphoma of central nervous system
  • 2A81.6 – Epstein-Barr Virus-positive diffuse large B-cell lymphoma of the elderly
  • 2A81.7 – Diffuse large B-cell lymphoma associated with chronic inflammation
  • 2A81.8 – ALK-positive large B-cell lymphoma
  • 2A81.9 – Primary effusion lymphoma
  • 2A81.A – Primary cutaneous diffuse large B-cell lymphoma, leg type
  • 2A81.Y – Other specified diffuse large B-cell lymphomas
  • 2A81.Z – Diffuse large B-cell lymphoma, not otherwise specified

Sibling codes

  • 2A80 – Follicular lymphoma
  • 2A82 – Mature B-cell neoplasm with leukaemic behaviour
  • 2A83 – Plasma cell neoplasms
  • 2A84 – Heavy chain diseases or malignant immunoproliferative diseases
  • 2A85 – Other specified mature B-cell neoplasms or lymphoma
  • 2A86 – B-cell lymphoma, mixed features
  • 2A8Z – Mature B-cell neoplasms, unspecified

Foundation entity

Diffuse large B-cell lymphomas – http://id.who.int/icd/entity/1946973604

Allowed postcoordination axes

Part of: 02: Neoplasms