2A84

ICD-11 MMS 2026-01

Heavy chain diseases or malignant immunoproliferative diseases

Description

A group of rare disorders of immunoglobulin synthesis associated with B-cell proliferative disorders that produce monoclonal heavy chains and typically no light chains.

Exclusions from above levels

  • 2E03 – Malignant neoplasm metastasis in bone or bone marrow
  • http://id.who.int/icd/entity/501778925 – Malignant neoplasm metastasis in lymph nodes
  • http://id.who.int/icd/entity/97145147 – Malignant neoplasm metastasis in thymus gland

Child codes

  • 2A84.0 – Alpha heavy chain disease
  • 2A84.1 – Gamma heavy chain disease
  • 2A84.2 – Mu heavy chain disease
  • 2A84.Y – Other specified malignant immunoproliferative diseases
  • 2A84.Z – Heavy chain diseases, unspecified

Sibling codes

  • 2A80 – Follicular lymphoma
  • 2A81 – Diffuse large B-cell lymphomas
  • 2A82 – Mature B-cell neoplasm with leukaemic behaviour
  • 2A83 – Plasma cell neoplasms
  • 2A85 – Other specified mature B-cell neoplasms or lymphoma
  • 2A86 – B-cell lymphoma, mixed features
  • 2A8Z – Mature B-cell neoplasms, unspecified

Foundation entity

Heavy chain diseases or malignant immunoproliferative diseases – http://id.who.int/icd/entity/702525006

Allowed postcoordination axes

Part of: 02: Neoplasms