Synovial sarcoma, primary site

Description

A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Exclusions from above levels

2A01.1 – Mesenchymal tumour of meninges
2A02.1 – Tumours of cranial or paraspinal nerves
http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures

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http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Child codes

2B5A.0 – Synovial sarcoma of soft tissues of limb
2B5A.1 – Synovial sarcoma of respiratory or intra-thoracic organs
2B5A.Y – Synovial sarcoma, other specified primary site
2B5A.Z – Synovial sarcoma, unspecified primary site

Sibling codes

2B50 – Chondrosarcoma, primary site
2B51 – Osteosarcoma, primary site
2B52 – Ewing sarcoma, primary site
2B53 – Fibroblastic or myofibroblastic tumour, primary site
2B54 – Undifferentiated pleomorphic sarcoma, primary site
2B55 – Rhabdomyosarcoma, primary site
2B56 – Angiosarcoma, primary site
2B57 – Kaposi sarcoma, primary site
2B58 – Leiomyosarcoma, primary site
2B59 – Liposarcoma, primary site
2B5B – Gastrointestinal stromal tumour, primary site
2B5C – Endometrial stromal sarcoma, primary site
2B5D – Malignant mixed epithelial mesenchymal tumour, primary site
2B5E – Malignant nerve sheath tumour of peripheral nerves or autonomic nervous system, primary site
2B5F – Sarcoma, not elsewhere classified, primary site
2B5G – Myosarcoma of uterus, part not specified
2B5H – Well differentiated lipomatous tumour, primary site
2B5J – Malignant miscellaneous tumours of bone or articular cartilage of other or unspecified sites
2B5K – Unspecified malignant soft tissue tumours or sarcomas of bone or articular cartilage of other or unspecified sites
2B5Y – Other specified malignant mesenchymal neoplasms
2B5Z – Malignant mesenchymal neoplasm of unspecified type

Foundation entity

Synovial sarcoma, primary site – http://id.who.int/icd/entity/644500343

Allowed postcoordination axes

Part of: 02: Neoplasms