5B5B

ICD-11 MMS 2026-01

Vitamin B2 deficiency

Description

The signs of riboflavin deficiency are sore throat, hyperaemia, oedema of the pharyngeal and oral mucous membranes, cheilosis, angular stomatitis, glossitis, seborrheic dermatitis, and normochromic normocytic anaemia associated with pure red cell cytoplasia of the bone marrow. The major cause of hyporiboflavinosis is inadequate dietary intake as a result of limited food supply, which is sometimes exacerbated by poor food storage or processing. Children in developing countries will commonly demonstrate clinical signs of riboflavin deficiency during periods of the year when gastrointestinal infections are prevalent. Decreased assimilation of riboflavin also results from abnormal digestion, such as that which occurs with lactose intolerance.

Index terms

  • Vitamin B2 deficiency
  • Ariboflavinosis
  • Hyporiboflavinosis
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  • Riboflavin deficiency

Inclusions

  • Riboflavin deficiency

Exclusions from above levels

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  • NF07.0 – starvation
  • 18 – Pregnancy, childbirth or the puerperium
  • http://id.who.int/icd/entity/1004987305 – Transitory endocrine or metabolic disorders specific to fetus or newborn

Foundation children elsewhere

  • 3A03.41 – Acquired riboflavin deficiency anaemia

Sibling codes

  • 5B50 – Underweight in infants, children or adolescents
  • 5B51 – Wasting in infants, children or adolescents
  • 5B52 – Acute malnutrition in infants, children or adolescents
  • 5B53 – Stunting in infants, children or adolescents
  • 5B54 – Underweight in adults
  • 5B55 – Vitamin A deficiency
  • 5B56 – Vitamin C deficiency
  • 5B57 – Vitamin D deficiency
  • 5B58 – Vitamin E deficiency
  • 5B59 – Vitamin K deficiency
  • 5B5A – Vitamin B1 deficiency
  • 5B5C – Vitamin B3 deficiency
  • 5B5D – Vitamin B6 deficiency
  • 5B5E – Folate deficiency
  • 5B5F – Vitamin B12 deficiency
  • 5B5G – Biotin deficiency
  • 5B5H – Pantothenic acid deficiency
  • 5B5J – Choline deficiency
  • 5B5K – Mineral deficiencies
  • 5B70 – Essential fatty acid deficiency
  • 5B71 – Protein deficiency
  • 5B7Y – Other specified undernutrition
  • 5B7Z – Unspecified undernutrition

Foundation entity

Vitamin B2 deficiency – http://id.who.int/icd/entity/1569514773

Part of: 05: Endocrine, nutritional or metabolic diseases