5B5D

ICD-11 MMS 2026-01

Vitamin B6 deficiency

Description

A deficiency of vitamin B6 alone is uncommon because it usually occurs in association with a deficit in other B-complex vitamins. Hypovitaminosis B6 may often occur with riboflavin (vitamin B2) deficiency. The classical clinical symptoms of vitamin B6 deficiency are a seborrheic dermatitis, microcytic anaemia, epileptiform convulsions, and depression and confusion. Infants are especially susceptible to insufficient intakes, which can lead to epileptiform convulsions. Moreover, there is usually a decrease in circulating lymphocytes and sometimes a normocytic, microcytic, or sideroblastic anaemia as well. As is the case with other micronutrient deficiencies, vitamin B6 deficiency results in an impairment of the immune system. Several medical conditions can also affect vitamin B6 metabolism and thus lead to deficiency symptoms.

Index terms

  • Vitamin B6 deficiency
  • pyridoxal deficiency
  • pyridoxamine deficiency
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  • pyridoxine deficiency
  • vitamin B6 deficiency syndrome
  • Peripheral neuropathy due to vitamin B6 deficiency
  • Peripheral neuropathy due to vitamin pyridoxine deficiency

Excludes

  • 3A72.1 – Pyridoxine-responsive sideroblastic anaemia, not elsewhere classified

Exclusions from above levels

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  • NF07.0 – starvation
  • 18 – Pregnancy, childbirth or the puerperium
  • http://id.who.int/icd/entity/1004987305 – Transitory endocrine or metabolic disorders specific to fetus or newborn

Foundation children elsewhere

  • 3A03.40 – Acquired pyridoxine deficiency anaemia

Sibling codes

  • 5B50 – Underweight in infants, children or adolescents
  • 5B51 – Wasting in infants, children or adolescents
  • 5B52 – Acute malnutrition in infants, children or adolescents
  • 5B53 – Stunting in infants, children or adolescents
  • 5B54 – Underweight in adults
  • 5B55 – Vitamin A deficiency
  • 5B56 – Vitamin C deficiency
  • 5B57 – Vitamin D deficiency
  • 5B58 – Vitamin E deficiency
  • 5B59 – Vitamin K deficiency
  • 5B5A – Vitamin B1 deficiency
  • 5B5B – Vitamin B2 deficiency
  • 5B5C – Vitamin B3 deficiency
  • 5B5E – Folate deficiency
  • 5B5F – Vitamin B12 deficiency
  • 5B5G – Biotin deficiency
  • 5B5H – Pantothenic acid deficiency
  • 5B5J – Choline deficiency
  • 5B5K – Mineral deficiencies
  • 5B70 – Essential fatty acid deficiency
  • 5B71 – Protein deficiency
  • 5B7Y – Other specified undernutrition
  • 5B7Z – Unspecified undernutrition

Foundation entity

Vitamin B6 deficiency – http://id.who.int/icd/entity/952576129

Allowed postcoordination axes

Part of: 05: Endocrine, nutritional or metabolic diseases