8A43.4

ICD-11 MMS 2026-01

Single optic neuritis aquaporin-4 antibody positive

Description

A single episode of optic neuritis associated with seropositivity for aquaporin-4 antibodies but without sufficient features to fulfill the 2006 NMO diagnostic criteria.

Index terms

  • Single optic neuritis aquaporin-4 antibody positive
  • Autoimmune aquaporin-4 channelopathy
  • Single optic neuritis, autoimmune aquaporin-4
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  • isolated AQP-4 positive optical neuritis
  • isolated optical aquaporin-4 positive optical neuritis

Exclusions from above levels

  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
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  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • 8A43.0 – Neuromyelitis optica aquaporin-4 antibody positive
  • 8A43.1 – Neuromyelitis optica aquaporin-4 antibody negative
  • 8A43.2 – Single transverse myelitis aquaporin-4 antibody positive
  • 8A43.3 – Recurrent transverse myelitis aquaporin-4 antibody positive
  • 8A43.5 – Recurrent optic neuritis aquaporin-4 antibody positive
  • 8A43.Y – Other specified neuromyelitis optica
  • 8A43.Z – Neuromyelitis optica, unspecified

Foundation entity

Single optic neuritis aquaporin-4 antibody positive – http://id.who.int/icd/entity/1119109040

Part of: 8A43: Neuromyelitis optica › 08: Diseases of the nervous system