CA21.1

ICD-11 MMS 2026-01

Panlobular emphysema

Description

Panlobular (panacinar) emphysema destroys the entire alveolus uniformly and is predominant in the lower half of the lungs. Panlobular emphysema generally is observed in patients with homozygous alpha1-antitrypsin deficiency.

Index terms

  • Panlobular emphysema
  • Panacinar emphysema

Inclusions

  • Panacinar emphysema

Exclusions from above levels

  • CA22 – emphysema with chronic (obstructive) bronchitis
  • CA22.1 – emphysematous (obstructive) bronchitis
  • CA81.Y – emphysema due to inhalation of chemicals, gases, fumes or vapours
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  • CB40.3 – emphysema mediastinal
  • CB40.4 – Compensatory emphysema
  • KB27.0 – Interstitial emphysema originating in the perinatal period
  • NE81 – emphysema, surgical (subcutaneous)
  • NF0A.7 – Traumatic subcutaneous emphysema, not elsewhere classified
  • 01 – Certain infectious or parasitic diseases
  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 19 – Certain conditions originating in the perinatal period
  • 20 – Congenital malformations, deformations and chromosomal abnormalities
  • 22 – Injury, poisoning or certain other consequences of external causes

Sibling codes

  • CA21.0 – MacLeod syndrome
  • CA21.2 – Centrilobular emphysema
  • CA21.Y – Other specified emphysema
  • CA21.Z – Emphysema, unspecified

Foundation entity

Panlobular emphysema – http://id.who.int/icd/entity/1480198053

Part of: CA21: Emphysema › 12: Diseases of the respiratory system