3A51.0

ICD-11 MMS 2026-01

Sickle cell trait

Description

A disease caused by genetic inheritance of one abnormal allele of the haemoglobin gene. This disease does not display the severe symptoms of sickle cell disease that occurs in homozygous individuals. Confirmation is by identification of mutation through genetic testing.

Index terms

  • Sickle cell trait
  • AS - [sickle cell trait]
  • Hb-S - [sickle cell haemoglobin] carrier
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  • HbAS - [heterozygous haemoglobin S]
  • HbAS - [sickle cell haemoglobin trait]
  • Sickle-cell disease carrier
  • haemoglobin a-s genotype
  • haemoglobin sickle cell trait disorder
  • heterozygous sickle cell trait
  • sickle cell haemoglobin trait
  • sickle-cell heterozygous disorder
  • sickle-cell trait haemoglobin disease

Exclusions from above levels

  • 04 – Diseases of the immune system
  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth or the puerperium
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  • 19 – Certain conditions originating in the perinatal period
  • 20 – Congenital malformations, deformations or chromosomal abnormalities
  • 22 – Injury, poisoning or certain other consequences of external causes
  • http://id.who.int/icd/entity/1000704511 – Human immunodeficiency virus disease
  • JB64.1 – Other diseases of the blood or blood-forming organs or certain disorders involving the immune mechanism complicating pregnancy, childbirth or the puerperium

Sibling codes

  • 3A51.1 – Sickle cell disease without crisis
  • 3A51.2 – Sickle cell disease with crisis
  • 3A51.3 – Compound heterozygous sickling disorders without crisis
  • 3A51.4 – Compound heterozygous sickling disorders with crisis
  • 3A51.5 – Haemoglobin C disease
  • 3A51.6 – Haemoglobin D disease
  • 3A51.7 – High affinity haemoglobin
  • 3A51.8 – Low affinity haemoglobin
  • 3A51.9 – Haemoglobin O disease
  • 3A51.A – Haemoglobin E disease
  • 3A51.B – Haemoglobin C/beta thalassaemia compound heterozygosity
  • 3A51.Y – Other specified sickle cell disorders or other haemoglobinopathies
  • 3A51.Z – Sickle cell disorders or other haemoglobinopathies, unspecified

Foundation entity

Sickle cell trait – http://id.who.int/icd/entity/2011497038

Part of: 3A51: Sickle cell disorders or other haemoglobinopathies › 03: Diseases of the blood or blood-forming organs