3A51

ICD-11 MMS 2026-01

Sickle cell disorders or other haemoglobinopathies

Description

Any disorder caused by a HbS mutation in the haemoglobin gene. This disorder is characterised by abnormal rigid sickle-shaped red blood cells decreasing its ability to carry oxygen. This disorder may present with fatigue, shortness of breath, dizziness, headaches, pallor of skin or mucous membranes, and jaundice. This disorder is confirmed by identification of HbS mutation by genetic testing.

Exclusions from above levels

  • 04 – Diseases of the immune system
  • 05 – Endocrine, nutritional or metabolic diseases
  • 18 – Complications of pregnancy, childbirth or the puerperium
Show allHide
  • 19 – Certain conditions originating in the perinatal period
  • 20 – Congenital malformations, deformations or chromosomal abnormalities
  • 22 – Injury, poisoning or certain other consequences of external causes
  • http://id.who.int/icd/entity/1000704511 – Human immunodeficiency virus disease
  • JB64.1 – Other diseases of the blood or blood-forming organs or certain disorders involving the immune mechanism complicating pregnancy, childbirth or the puerperium

Child codes

  • 3A51.0 – Sickle cell trait
  • 3A51.1 – Sickle cell disease without crisis
  • 3A51.2 – Sickle cell disease with crisis
  • 3A51.3 – Compound heterozygous sickling disorders without crisis
  • 3A51.4 – Compound heterozygous sickling disorders with crisis
  • 3A51.5 – Haemoglobin C disease
  • 3A51.6 – Haemoglobin D disease
  • 3A51.7 – High affinity haemoglobin
  • 3A51.8 – Low affinity haemoglobin
  • 3A51.9 – Haemoglobin O disease
  • 3A51.A – Haemoglobin E disease
  • 3A51.B – Haemoglobin C/beta thalassaemia compound heterozygosity
  • 3A51.Y – Other specified sickle cell disorders or other haemoglobinopathies
  • 3A51.Z – Sickle cell disorders or other haemoglobinopathies, unspecified

Foundation children elsewhere

  • FB81.4 – Osteonecrosis due to haemoglobinopathy

Sibling codes

  • 3A50 – Thalassaemias
  • 3A70 – Aplastic anaemia
  • 3A71 – Anaemia due to chronic disease
  • 3A72 – Sideroblastic anaemia
  • 3A73 – Congenital dyserythropoietic anaemia
  • 3A90 – Anaemia due to acute disease
  • 3A91 – Congenital methaemoglobinaemia
  • 3A92 – Hereditary methaemoglobinaemia
  • 3A93 – Acquired methaemoglobinaemia
  • 3A94 – Acute posthaemorrhagic anaemia
  • 3A9Y – Other specified anaemias or erythrocyte disorders
  • 3A9Z – Anaemias or other erythrocyte disorders, unspecified

Foundation entity

Sickle cell disorders or other haemoglobinopathies – http://id.who.int/icd/entity/975559344

Allowed postcoordination axes

Part of: 03: Diseases of the blood or blood-forming organs