4A42ICD-11 MMS 2026-01
Systemic sclerosis
Description
Systemic sclerosis is a systemic disorder of the connective tissue; manifested by hardening and thickening of the skin, by abnormalities involving the microvasculature and larger vessels, and by fibrotic degenerative changes in various body organs including the heart, lungs, kidneys, and gastrointestinal tract.
Inclusions
- Systemic scleroderma
Excludes
EB61.0– Circumscribed scleroderma
Exclusions from above levels
Child codes
Sibling codes
4A40– Lupus erythematosus4A41– Idiopathic inflammatory myopathy4A43– Overlap or undifferentiated nonorgan specific systemic autoimmune disease4A44– Vasculitis4A45– Antiphospholipid syndrome4A4Y– Other specified nonorgan specific systemic autoimmune disorders4A4Z– Nonorgan specific systemic autoimmune disorders, unspecified
Foundation entity
Systemic sclerosis – http://id.who.int/icd/entity/1084365812
Allowed postcoordination axes
Part of: 04: Diseases of the immune system